Tuesday could be a historic Election Day — voters might elect Hillary Clinton as the nation's first female president. California voters could also make some significant changes to state laws. Here's what you need to know.

Some 46.26 million people nationwide have already cast their ballots, according to The Huffington Post.

According to the LA County Registrar, 25,474 early votes were cast at polling stations in Los Angeles County over the past two weekends.

For the first time in 24 years, there is a U.S. Senate race in California without an incumbent on the ballot. State Attorney General Kamala Harris and U.S. Rep. Loretta Sanchez are battling for the seat vacated by retiring Sen. Barbara Boxer.

Both women are Democrats, and the race marks California's first U.S. Senate contest with no Republican on the general election ballot since the state began direct election of senators in 1914. Harris would be the first biracial woman and first Indian-American woman in the U.S. Senate, while Sanchez would be the first Latina, according to Politico. Kamala Harris made a campaign stop at USC on Monday. Loretta Sanchez campaigned downtown.

California voters are also deciding on 17 statewide propositions this year, the most on any ballot since March 2000, according to the LA Times.

Here is an overview of some of the most talked-about issues on the ballot in California and Los Angeles:

Legalization of marijuana: Proposition 64 would legalize the recreational use of marijuana for people aged 21 and over. Marijuana consumption would be permitted in private residences, and users would be allowed to legally possess up to one ounce of marijuana.

Death penalty: Propositions 62 and 66 are two initiatives dealing with the death penalty. If both pass, the one with the most votes will override the other. Prop. 62 bans the use of the death penalty and replaces it with life imprisonment without parole. It would also be applied retroactively. Prop. 66 would keep the death penalty in place and accelerate its process, capping at five years the amount of time that those sentenced can challenge the punishment.

Cigarette tax: Proposition 56 would increase the tax on tobacco by $2. While supporters hope that the price increase will discourage Californians from buying tobacco products, opponents call the tax a grab by insurance companies.

Bilingual education: Proposition 58 would allow bilingual teaching in California public schools again. If passed, Prop. 58 would void a 1998 ballot initiative that restricted multilingual education in the state.

Drug prices: Proposition 61 would regulate the price of drugs in California. It would require California to negotiate with drug companies to change the cost of drugs to the same price point as that of the U.S. Department of Veterans Affairs. The DVA negotiates the price points of drugs for millions of veterans and allows their customers to pay usually 20 percent less than the government price. While many Veterans Affairs groups oppose the measure, Vermont Sen. Bernie Sanders, who ran for the Democratic presidential nomination, is a strong proponent and campaigned for it in Los Angeles this week.

Gun control: Proposition 63 deals with gun control. The ballot measure would put restrictions on buying ammunition by requiring background checks and making it harder to purchase ammunition outside of California. It would also prohibit the possession of large-capacity magazines and mandate that people who are prohibited from owning a gun to turn in firearms to local law enforcement. Gun owners and dealers would also have to quickly report a theft or loss. If the proposition passes, stealing a gun would become a felony.

Plastic bags: Propositions 65 and 67 both deal with plastic bags. Prop. 65 would require stores to direct money collected by sales of carry-out bags to specified environmental projects. Proponents say the bag fees paid by shoppers should go to the environment, not into grocers' pockets, while opponents say Prop. 65 is sponsored by out-of-state plastic companies.

Prop. 67, also known as the California Plastic Bag Ban Veto Referendum, would ratify Senate Bill 270, which prohibits grocery stores and pharmacies from providing single-use plastic bags. Paper bags would still be available for 10 cents.

In addition to the state propositions, here are some local measures that voters in LA County will decide:

Measure HHH is a Los Angeles measure dealing with homelessness. It would provide $1.2 billion over 10 years to finance the construction of affordable housing projects for the homeless. The measure has garnered the support of Los Angeles Mayor Eric Garcetti and several City Council members, and has huge support from homeless advocates.

Measure JJJ is a Los Angeles measure dealing with affordable housing. It's an inclusionary zoning policy. JJJ aims to create more low-income housing by requiring new developments of 10 units or more to ensure up to 20 percent of living spaces meet affordable housing requirements.

Measure M is a Los Angeles measure dealing with transportation and infrastructure. It's a permanent sales tax increase that would go towards transportation projects across LA.

Need to vote? Find your polling place here. You can bring in a vote-by-mail ballot to any polling location if you forgot to mail it in. Polls close at 8 p.m. this evening.

A previous version of this story misstated what is taxed in Proposition 56. The proposition would tax tobacco products.